Generation of integration-free induced pluripotent stem cell lines from four pediatric ADHD patients
نویسندگان
چکیده
Human induced pluripotent stem cell (iPSC) lines have been derived from four male patients with childhood attention-deficit hyperactivity disorder (ADHD). Children and adolescents between the ages 6 18 suffering ADHD were recruited for this work. Isolated keratinocytes or peripheral blood mononuclear cells participants reprogrammed into iPSCs using non-integrating Sendai virus to deliver reprogramming factors Oct3/4, Sox2, Klf4 c-Myc.
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ژورنال
عنوان ژورنال: Stem Cell Research
سال: 2021
ISSN: ['1876-7753', '1873-5061']
DOI: https://doi.org/10.1016/j.scr.2021.102268